| Portland Trail Blazers | National Basketball Association | Portland | 1970 | Veterans Memorial Coliseum, Moda Center |
| Potenza 84 | — | Potenza | — | — |
| Quebec Bulldogs | — | — | 1888 | Quebec Skating Rink |
| Racing de Huamachuco | Copa Perú | — | 1946 | — |
| Raggisolaris Faenza | — | Faenza | — | — |
| Real Salt Lake | Major League Soccer | Salt Lake City | 2005 | America First Field |
| Real Sebastiani Rieti | Serie A2 | Rieti | 2020 | — |
| Regatas Lima | Copa Perú | — | — | — |
| Riviera Vado Basket | — | — | — | — |
| Robur Basket Osimo | — | Osimo | — | — |
| Robur et Fides Varese | — | Varese | — | — |
| Ruvo di Puglia Basket | — | — | — | — |
| Sacramento Kings | National Basketball Association | Sacramento | 1945 | ARCO Arena I, Sleep Train Arena, Golden 1 Center, Municipal Auditorium, Kemper Arena, Omaha Civic Auditorium, Cincinnati Gardens, Edgerton Park Arena, Blue Cross Arena |
| Saetas de Oro | Copa Perú | — | — | — |
| Saint Louis City SC | Major League Soccer | Saint Louis | 20 agosto 2019 | Energizer Park |
| Salerno Basket 92 | — | — | — | — |
| San Antonio Spurs | National Basketball Association | — | 1967 | Alamodome, Kay Bailey Hutchison Convention Center, HemisFair Arena, Centro convegni di Fort Worth, Frost Bank Center, Moody Coliseum, Lubbock Municipal Coliseum |
| San Diego FC | Major League Soccer | San Diego | 18 maggio 2023 | Snapdragon Stadium |
| San Diego Padres | Major League Baseball | San Diego | 1969 | Petco Park |
| San Francisco 49ers | National Football League | — | 1946 | Levi's Stadium |
| San Francisco de Asís de Lonya Grande | Copa Perú | — | 1946 | — |
| San Francisco Giants | Major League Baseball | San Francisco | 1883 | Oracle Park |
| San Jose Earthquakes | Major League Soccer | San Jose | 1995 | Avaya Stadium, Buck Shaw Stadium |
| San Jose Sharks | — | — | 1991 | Cow Palace, SAP Center at San Jose |
| San Lorenzo de Almagro de Chiclayo | Copa Perú | — | — | Estadio Elías Aguirre |
| San Martín de Porres de Pucallpa | Copa Perú | — | 9 aprile 1964 | Estadio Aliardo Soria Pérez |
| San Raffaele Basket | — | — | 1978 | — |
| San Simón de Moquegua | Campeonato Descentralizado | — | 1983 | Estadio 25 de Noviembre |
| Santa Marinella Basket | — | — | — | — |
| Santiago Barranco | Copa Perú | — | 20 settembre 1929 | — |
| Santos de Nasca | Copa Perú | — | — | Estadio José Picasso Peratta |
| Scaligera Basket Verona | Serie A | Verona | 1951 | PalaOlimpia |
| Seattle Kraken | — | — | 2021 | Climate Pledge Arena |
| Seattle Mariners | Major League Baseball | — | 1977 | Kingdome, T-Mobile Park |
| Seattle Metropolitans | Pacific Coast Hockey League | Seattle | 1915 | — |
| Seattle Seahawks | National Football League | — | 1976 | Kingdome, Husky Stadium, Lumen Field |
| Seattle Sounders FC | Major League Soccer | Seattle | 2009 | Lumen Field |
| Seattle SuperSonics | — | Washington | 1967 | Kingdome, Climate Pledge Arena, Tacoma Dome |
| Sebastiani Basket Club Rieti | — | — | — | — |
| Senati FBC | Copa Perú | — | — | Estadio Mariano Melgar |
| Serrato Pacasmayo | Segunda División | — | 2012 | Estadio Carlos A. Olivares |
| Sisv Viterbo | — | Viterbo | — | — |
| Società Cestistica Mazzini | — | Bologna | — | — |
| Società Sportiva Basket Napoli | — | Napoli | 1946 | PalaBarbuto |
| Società Sportiva Felice Scandone | Serie B Nazionale | Avellino | 1948 | Palasport Giacomo Del Mauro |
| Sport Boys Association | Torneo Descentralizado | — | 1927 | Estadio Miguel Grau |
| Sport Chorrillos | Copa Perú | — | — | Estadio Campeones del 36 |
| Sport Club Alcamo | — | Alcamo | — | — |